This second joint meeting of the UK RAPID and US AMOC science programs provides an opportunity to explore new results from the purposefully designed AMOC observing systems, as well as a wide variety of observational, global coupled and regional model studies and theory in this rapidly changing field of research. The meeting is intended to span the full breadth of AMOC research: paleo- and modern observational studies, theory, modelling, predictability/prediction, and climate impacts.